The Pauling Lab - Computational Lipidomics

Our aim is to bring lipidomics to the playbook of systems medicine for the next generation of precision medicine.
To learn more about our research visit our website:

Dr. Josch Pauling

I'm a TUM junior research fellow and a ZD.B group leader at the Chair of Experimental Bioinformatics. My group works on computational lipidomics. We develop the platform LipiTUM and concentrate on analyzing and identifying lipid species in MS2+ spectra. Our aim is to bring the lipid metabolism on the playbook of systems biomedicine and, thus, to unravel novel kinds of targets for the next generation of precision medicine. I studied bioinformatics in Bielefeld, Germany, and worked as research assistant at the Max Planck Institute for Informatics. I gained my PhD for the University of Southern Denmark, and did a postdoc at the Humboldt University of Berlin in the lab of Edda Klipp.


Kundai Sachikonye

I am a PhD student in the Pauling Lab working on the LipiTUM project aimed at developing methods for the identification and quantification of lipid species in LC-MS/MS. I did my bachelors in Biochemistry and Cell Biology at Jacobs University Bremen and graduate studies in Pharmaceutical Biotechnology and Bioinformatics at HAW Hamburg, UKE Hamburg and Eberhard Karls Universitaet Tübingen. I have done internships in LC-MS/MS-related topics at UZ (Zimbabwe), Forschungs und Transferzentrum Bioprocess Hamburg, University of Groningen (Netherlands), UKE Hamburg, Leibniz Lungenzentrum Borstel and Fraunhofer IGB Stuttgart. 


Tim Rose

My name is Tim Rose. I'm a PhD student in the LipiTUM group. I received my Bachelor's degree in Quantitative Biology in Düsseldorf, where I did my thesis on equilibrium behavior of the Pentose Phosphate Pathway. After that, I worked on a master's project in modeling of radiation response of cancer cells to obtain a M.Sc. degree in Biophysics.
My research interests are analysis and modeling of multi-omics data, development of software tools for simulations/analysis and HPC. I think the utilization of multi-omics data is the key to infer the complexity of cells and get an understanding of how the different levels relate to each other and result in a specific phenotype. In my PhD project I work on data mining, analysis pipelines and the integration of lipidomics with other omics data.


Lisa Falk

My name is Lisa Falk, a master student in Molecular Biotechnology with a background in Bioinformatics. I received my Bachelor’s degree at the University of Tübingen with a thesis on Qualitative Models. As a HiWi I contribute to existing projects. Currently, I work with lipid related databases, extract and map relevant data and make them easier accessible.

Nikolai Köhler

My name is Nikolai Köhler. I'm a master student in Molecular Biotechnology at TUM with a special interest in bioinformatics and biochemical analytics. Through an internship at the University of Melbourne/Metabolomics Australia I gained practical experience in MS-based lipidomics analysis and the current computational and analytical challenges. I recently joined the group as a HiWi to participate in and contribute to ongoing collaborations and I will do a research project, in which I will develop a scoring method for spectrum matches for the LipiTUM platform.

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Chair of Experimental Bioinformatics

TUM School of Life Sciences Weihenstephan

Technical University of Munich

Tel: +49-8161-71-2136

E-Mail: exbio[a.t_))

Office: OG-L06